Discover Protein Variants with Unmatched Precision on Platinum®

Dive into the intricacies of protein variants using Next-Generation Protein Sequencing™ on Platinum .

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Applications Protein Variant

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Utilizing Next-Generation Protein Sequencing with single-molecule resolution in a streamlined workflow, Quantum-Si’s Platinum advances proteomic discoveries by detecting variants in your laboratory

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Dive into our application notes to grasp how Platinum’s next-generation sequencing optimizes protein variant detection with unparalleled precision.

  • Quantum-Si’s Next Generation Protein Sequencing Technology Enables Rapid and Accurate Distinction of Variants of the SARS-CoV-2 Virus – APP NOTE

    This application note showcases Quantum-Si’s protein sequencing technology on the Platinum instrument, which enables the rapid and accurate distinction of variants of the SARS-CoV-2 virus based on differences in the amino acid sequence of their Spike proteins. By identifying and tracking these variants, scientists can better understand their impact on public health and develop effective treatments and vaccines.

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    Focusing on a key mutation, we observed the distinctive kinetic influences on recognizer binding. The clear differences in pulse durations (PD) between the peptides of interest highlight the power of Quantum-Si’s Platinum instrument in differentiating the Alpha variant from the Delta and Omicron variants through a single mutation.

    Here we highlight the differentiation of the Omicron variant from the Alpha and Delta variants based on the detection of a single peptide. The capability to identify variant-specific peptides contributes to the accurate and precise distinction of SARS-CoV-2 variants using Quantum-Si’s Platinum instrument.