An Accessible Next-Gen Protein Sequencer™ for Deeper Analysis
Transform how you sequence and analyze proteins at the single-molecule level. Platinum® Pro offers protein analysis with single-molecule precision. With single-molecule sequencing and real-time kinetic insights, it delivers a streamlined, cost-effective workflow to accelerate discoveries in proteomics.
Upgrade Proteomics with Platinum Pro
Platinum Pro sets a new standard in single-molecule proteomics, enabling high-sensitivity detection of proteins and analysis of proteoforms. Its compact design and accessible workflow empower every lab to unlock deeper insights into protein structure and function.
Accessible Proteomics
Compact Benchtop Instrument
Space-saving design for any lab
Cost-effective Solution
High value without the complexity
No Expertise Needed
Simplified workflows make sequencing
easy for all researchers
Next-level Insights
Single-molecule Resolution
Precision sequencing down to single amino acids
Deep Proteoform Interrogation
Detect and analyze protein variants and post-translational modifications
Direct Protein Detection Method
Real-time kinetic insights for unparalleled accuracy
Platinum® Pro NGPS™
Traditional Mass Spec
Directly sequences proteins at single-molecule resolution using a simplified, benchtop platform with no antibodies, or complex workflows required
Infers protein sequences through indirect, multi-step processes that often require specialized expertise and infrastructure
Detects single-amino acid changes with unmatched precision
Relies on peptide fragmentation and reconstruction
No labeling, ionization, or chromatography steps
Requires antibodies, ionization, and chromatography
Compatible with standard lab environments
Complex data analysis and interpretation
Integrated workflow from prep to analysis
Limited resolution for isobaric and modified residues
Designed for Real-world Applications
-
Protein Barcoding: Speed up your research by profiling multiple protein samples at once, improving throughput and screening efficiency -
Protein Identification: Confidently detect and verify proteins in complex samples with high sensitivity and single-amino acid resolution -
Protein Variant Detection: Uncover key biological insights by identifying subtle amino acid substitutions and resolving isobaric variants -
Post-translational Modification Analysis: Map and measure regulatory protein modifications with precision to understand functional changes -
Antibody Sequencing and Characterization: Maximize therapeutic development by analyzing antibody specificity, binding affinity, and sample purity -
Biomarker Identification: Find and validate disease biomarkers with single-molecule precision to strengthen multiomic research
“Our data highlight Platinum’s ability to accurately distinguish all major types of proteoform variation within the TPM gene family, this provides a more precise window into complex protein families, and this capability to precisely sequence and distinguish peptide variations paves the way for numerous applications in disease research and biomarker discovery.”
Dr. Gloria Sheynkman, PhD
Assistant Professor at University of Virginia School of Medicine
Your Streamlined Steps to Proteomic Excellence
Prepare Proteins for Single-molecule Sequencing
Effortlessly prepare samples in less than three hours of hands-on time.
Sequence Proteins with Single-amino Acid Resolution
Achieve unmatched precision and speed with Platinum Pro.
Analyze Protein Sequencing Data with Ease
Leverage the power of Platinum Analysis software for proteomic data analysis.
Related Products and Services
Barcoding Solutions
Characterize multiple protein variants simultaneously using protein barcodes on Platinum Pro
Sequencing Solutions
Interrogate individual proteins with high resolution using Next-Gen Protein Sequencing™
Suggested Resources
Protein Barcoding Preprint Publication
Protein barcoding has emerged as a transformative tool for the multiplexed identification
Publication
Protein Sequencing With Single-Amino Acid Resolution Discerns Peptides That
Discriminate Tropomyosin Proteoforms
Preprint Publication
Detecting Amino Acid Variants Using Next-Gen Protein Sequencing (NGPS)
Publication
Real-Time Dynamic Single-Molecule Protein Sequencing on an Integrated
Semiconductor Device
Ready to bring Platinum Pro to your lab?
Request a quote or reach out with questions to learn how the Platinum Pro bench top instrument with Next-Gen Protein Sequencing can accelerate your research.
Platinum Pro Next-Generation Protein Sequencer™ FAQs
-
What types of labs can use Platinum® Pro?
Academic, biotech, and pharmaceutical labs can easily integrate Platinum® Pro into standard workflows without specialized equipment or proteomics expertise.
-
How is Platinum® Pro different from immunoassays?
Unlike immunoassays, Platinum® Pro does not rely on antibodies for detection, allowing broader protein identification and eliminating dependency on binding reagents.
-
How does the Platinum® Pro protein sequencer improve on Edman degradation?
Platinum® Pro avoids slow chemical cleavage steps, enabling faster, more sensitive protein sequencing without degradation-related limitations.
-
How does the Platinum® Pro protein sequencer enable direct protein sequencing?
It uses proprietary single-molecule technology to detect amino acids individually, eliminating the need for chemical cleavage, ionization, or antibody-based detection required by traditional proteomics methods.