Single-molecule Proteomics from the Benchtop
Quantum-Si brings the groundbreaking power of single-molecule protein sequencing to every lab, everywhere.
Platinum® Pro
An advanced benchtop protein sequencer delivering single-molecule resolution with real-time kinetic insights, enhanced data analysis, and a customizable user experience for variant detection and protein identification in a compact system.
-
Accessible Proteomics: No dedicated lab space or expertise required -
Simplified Workflow: Less than three hours of hands-on time -
Insight Generation: Direct detection of proteoforms and modifications -
User-friendly Interface: Enlarged touchscreen for intuitive operation -
Flexible Data Analysis: Supports both local and cloud-based processing
Breakthroughs from the Benchtop
Proteomics community findings enabled by single-molecule protein sequencing
PTMs
Explores how N-terminal amino acid recognizer-based sequencing can detect a variety of PTMs based on changes in recognizer kinetics
Pathogen Detection
Evaluates single-molecule protein sequencing to identify proteins from biological samples within 24 hours for biothreat, pathogen and toxin detection
Hemoglobin Variants
Demonstrates Quantum-Si’s single-molecule protein sequencing as a powerful approach for identifying clinically relevant Hb variants from whole blood
Single-molecule Protein Sequencing Applications
Post-translational Modification Analysis
Precisely analyze proteoforms and post-translational modifications (PTM) to gain deeper functional insights into protein regulation and activity.
Protein Identification
Achieve single-amino acid resolution for precise protein characterization, and validation in research and diagnostics.
Protein Variants
Detect amino acid substitutions and isobaric variations with single-molecule resolution, uncovering critical insights into health and disease.
Protein Barcoding
Simultaneously characterize multiple protein variants with barcoding, increasing throughput and improving efficiency in screening and therapeutic development.
Antibody Sequencing and Characterization
Gain deep insights into antibody specificity, affinity, and purity. This advanced approach ensures precise targeting and maximized efficacy in therapeutic development.
Single-molecule Protein Sequencing Technology
Harness kinetic signatures to sequence proteins and detect proteome changes. Quantum-Si’s single-molecule protein sequencing simplifies sequencing compared to Edman degradation, dives deeper than mass spectrometry with single-molecule resolution, and detects amino acid-level changes missed by immunoassays, making it a powerful tool for identifying protein variants and modifications.
-
Single-molecule Resolution Captures amino acid sequences with unmatched detail -
Modification Detection Identifies post-translational changes in real time -
Broad Applicability Supports research in biomarker discovery, disease mechanisms, and drug development -
Streamlined Workflow Minimizes reliance on antibodies and mass spectrometry
Unleash the Power of Protein Barcoding in Drug Development
Quantum-Si’s Platinum Pro is revolutionizing proteomics in pharmaceutical development with protein barcoding, enabling multiplexed protein variant screening and characterization with faster assay speeds and enhanced throughput.
Accelerated Drug Delivery Development
Streamlines screening of delivery vehicles like lipid nanoparticles (LNPs) and adeno-associated virus (AAV) capsids in vivo, enhancing precision and speed in discovery programs.
Comprehensive Variant Analysis
Enables precise tracking and characterization of protein variants from CRISPR and directed evolution, supporting targeted therapy development.
Enhanced Protein Interaction Studies
Provides in-depth analysis of protein trafficking and interactions, offering crucial insights into cellular mechanisms for drug development.
NEXT-GENERATION PROTEIN
SEQUENCING TECHNOLOGY
INNOVATION LEADERSHIP
2023 PROTEOMICS
COMPANY OF THE YEAR
INNOVATION BY
DESIGN 2023
About Quantum‑Si
Founded in 2013, Quantum-Si is pioneering the post-genomic era by making protein sequencing accessible. Their flagship products, Platinum and Platinum Pro are the world’s first next-gen protein sequencing instruments, enabling single-molecule, single-amino-acid resolution.
By integrating biology, chemistry, and artificial intelligence, Quantum-Si empowers researchers to study proteins at an unprecedented scale. This innovation is driving groundbreaking advancements in scientific research and drug development.
Publications
Latest Press Releases
June 10, 2026