Quantum-Si’s Next Generation Protein Sequencing Technology Enables Rapid and Accurate Distinction of Variants of the SARS-CoV-2 Virus


Accurate and rapid identification of SARS-CoV-2 variants is crucial for effective surveillance and disease monitoring. Furthermore, patients with long COVID may still have residual spike protein in their blood. Distinguishing variants in long COVID patients via protein sequencing could lead to new understandings and treatment of the disease. In this application note, we present a method utilizing Quantum-Si’s protein sequencing technology on the Platinum® instrument to distinguish the Alpha, Delta, and Omicron variants based on differences in the amino acid sequence of their Spike proteins.