Building on its foundation in insect, mammalian, and bacterial expression, OET has expanded its offering to include high-precision protein sequencing services powered by Quantum-Si’s Platinum® platform, helping bring next-generation protein analysis to a broader range of researchers and drug developers.
We’re thrilled to spotlight the first winner of our Pioneer Grant, Resha Rajkarnikar, a graduate student in Mythreye Karthikeyan’s lab at the University of Alabama at Birmingham. Resha’s project focuses on an exciting and understudied area of cancer biology: the regulation and functional role of mitogen-activated protein kinase 15 (MAPK15) in ovarian cancer.
Next-gen protein sequencing (NGPS) is poised to transform our ability to study ncORFs. Traditional proteomics methods can struggle to detect tiny or low-abundance proteins. In contrast, NGPS can bridge the gap between genomic data and functional proteins, allowing researchers to detect smaller peptides and translate ncORFs more effectively.
Next-gen protein sequencing (NGPS) is poised to transform our ability to study ncORFs. Traditional proteomics methods can struggle to detect tiny or low-abundance proteins. In contrast, NGPS can bridge the gap between genomic data and functional proteins, allowing researchers to detect smaller peptides and translate ncORFs more effectively.
Next-gen protein sequencing (NGPS) is poised to transform our ability to study ncORFs. Traditional proteomics methods can struggle to detect tiny or low-abundance proteins. In contrast, NGPS can bridge the gap between genomic data and functional proteins, allowing researchers to detect smaller peptides and translate ncORFs more effectively.
December 2, 2024 • Meredith Carpenter, PhD – Head of Scientific Affairs Imagine a world where we can unravel the intricate details of protein diversity with single-molecule precision. This vision is becoming a reality thanks to a recently released preprint publication on bioRxiv from Dr. Gloria Sheynkman and her team at the University of Virginia […]
August 1, 2024 • Winston Timp, PhD In a 2020 article co-authored with his father,1 Dr. Timp noted that “The prevalence of heterogeneity in mRNA translation, posttranslational modifications (PTMs) and posttranslational structural processing are revealed only by direct protein-level analysis, and there is a pressing need for it.” At the time of the publication, proteomics relied mainly on a […]
By Brian Reed, PhD, Head of Research At the Festival of Genomics meeting held earlier this summer, Dr. Gloria Sheynkman, Assistant Professor at the University of Virginia, captivated a full audience with her presentation on the use of next-generation protein sequencing (NGPS) on the Quantum-Si Platinum® instrument to detect disease-relevant proteoforms. This significant interest in […]
By John Vieceli, PhD, SVP of Product Development Last week, Quantum-Si announced an exciting update to our suite of software tools, reaffirming our commitment to continually enhance next-generation protein sequencing (NGPS) for our customers. Following the introduction of the v2 sequencing kit in Q1, this Q2 software update marks another step forward. Additionally, we’ve pre-announced […]
By Jeff Hawkins The history of scientific research is mostly filled with periods of incremental progress, wherein seemingly disparate studies slowly—and sometimes unknowingly—chip away at conceptual and technological barriers. As these small moments of progress accumulate, they begin to reach a critical mass tipping point, one punctuated by the collapse of barriers and the sudden […]