Supreme Developer, Author at Quantum-Si

Quantum-Si’s Next-Gen Protein Sequencer Enables Protein Detection and Peptide Characterization

Summary: Sequencing proteins and correlating amino acid changes to biological function is critical to advancing our understanding of human health and disease. Next-generation protein sequencing (NGPS) on Platinum® enables researchers to identify and characterize proteins with single-molecule resolution in a simple workflow and on a benchtop instrument. To demonstrate the versatility of Platinum and the […]

Next-Gen Protein Sequencing: Interrogating Proteins with Single-molecule Amino Acid Resolution on Platinum®

Proteins are the workhorses of cells and provide vital insights to cell health and disease function. Immunoassays and mass spectrometry are well established methods for studying proteins and have led to important discoveries in human health and disease. However, these techniques either lack single-molecule resolution to interrogate each individual amino acid residue or require a […]

Unravel the Secrets of Human Disease with Next-Gen Protein Sequencing

Protein-level analyses are crucial to advancing human disease research. However, traditional proteomic methods often lack the accuracy, specificity and depth recorded at the genomic or transcriptomic level. The latest protein sequencing technology offers information-rich insights into the primary structure, interactions, and modifications of diverse proteins, supporting an understanding of biological function in human disease. This […]

Measuring Nanobody Kinetics at the Single-Molecule Level

Summary: Antibodies are a paradigm for high-affinity, protein-based binding reagents and are extremely important in biotechnological, diagnostic, and therapeutic applications. Of special interest are nanobodies, recombinant variable domains from heavy-chain-only antibodies. Nanobodies have several advantages: their small molecular weight, superior solubility and stability and clearance rate. One particular use of nanobodies is their use in […]

Multiplexing Nanobody Kinetics Measurements at the Single-Molecule Level

Summary: Single-molecule methods provide useful insights into the intermolecular variations and functional differences of individual molecules and have revealed much about the complexity of biological processes. Today it is possible to monitor binding kinetics at the single molecule level in a highly parallel fashion using zero-mode waveguide (ZMW) arrays. This allows monitoring the binding/unbinding of […]

Library Preparation Kit, V2 – Lys-C Data Sheet

Summary Easily prepare proteins for next-gen protein sequencing (NGPS) on Platinum® in a simple user-friendly workflow. The Platinum instrument, kits, and software contain everything you need to prepare, sequence, and analyze proteins. Library preparation is the initial step in Quantum-Si’s NGPS workflow. The Library Preparation Kit, V2 – Lys-C contains the necessary components to digest […]

Characterizing Far-Flung Extremophiles With Next-Gen Protein Sequencing

Extreme environments that harbor adapted bacteria are widespread — ranging from refrigerators to hot springs. Accordingly, there is massive industrial interest in identifying cold-active, solvent-tolerant, and heat-loving proteins. Thermophiles found in hot springs and the deep sea are sources of diverse biotechnological activity. However, access to compact instrumentation for interrogating proteins in these underexplored sites […]

Beyond the Genome: Unraveling Protein Variability with Quantum-Si’s Next-Gen Protein Sequencing Technology

Summary: Next-gen protein sequencing is a transformational tool for protein science to unlock new insights into the function of proteins in health and diseases. Quantum-Si’s Platinum® technology brings the insights of protein sequencing to every lab with a space-friendly benchtop instrument, a simple end-to-end workflow, and single-molecule resolution that enables detection of protein variants and […]

Quantum-Si Debuts New Headquarters in Branford, Connecticut

World-class laboratory and office space underpins the scaling of Quantum-Si’s operational and development capabilities in support of its goal to revolutionize protein sequencing. Company continues rich 10 year history in Connecticut with new facility through 2029 BRANFORD, Conn.–(BUSINESS WIRE)–Jun. 7, 2023– Quantum-Si- Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today […]

Quantum-Si to Participate at Two Upcoming Investor Conferences

GUILFORD, Conn.–(BUSINESS WIRE)– Jul. 29, 2022 —Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a life sciences company commercializing the first next generation single molecule protein sequencing platform, today announced that it will be participating in two upcoming investor conferences. Patrick Schneider, Quantum-Si’s President and Chief Operating Officer, will participate in fireside chats at […]