SelectScience Webinar 2024

In this webinar, Dr. Michael Caldwell, Scientific Officer at Northwestern Proteomics Center of Excellence, will explore top-down mass spectrometry (TD-MS) and Platinum®. Platinum is a benchtop instrument that provides single amino acid resolution of single protein molecules to characterize IL-6, including pyroglutamate (pE), a post-translational modification (PTM) produced via enzymatic and spontaneous cyclization of N-terminal glutamine (Q)/glutamate (E) residues.

Time: 9 AM PST | 12 PM EST | 5 PM BST

Harness the power of protein sequencing in your lab

Next-gen protein sequencing (NGPS) offers a unique means to investigate proteins at a level of resolution inaccessible with other technologies. Moreover, with advanced single-molecule protein sequencing technologies like Quantum-Si’s Platinum® Pro instrument, researchers can now reliably identify changes to proteins at the amino acid level. Download our latest eBook and explore how NGPS can advance […]

The image shows the word Yale in a blue serif font on a white background.

Single-molecule sequencing of immunopeptides and antigenic protein markers on the Platinum® instrument

Summary:  Single-molecule protein sequencing offers the sensitivity needed to explore the immunopeptidome and profile tumor-associated antigens. We demonstrate the use of the Platinum benchtop instrument to sequence immunopeptides and proteins at the single-molecule level. Peptides are loaded into nanoscale chambers on a chip, where dye-labeled N-terminal amino acid recognizers bind and generate distinct kinetic patterns. […]

Accelerate Protein Screening by Sequencing Protein Barcodes on Platinum®

Screening protein variants of interest is an essential step when studying mechanism of disease or developing novel biotherapeutics. Current screening methods require either back-to-back design-build-test cycles or large arrayed screens using automation, which can lead to lengthy assay timelines, technical challenges, unwanted variability and unnecessary cost. Furthermore, traditional phage-display or yeast-display methods may not be […]

University of Virginia logo with an orange Rotunda graphic on the left and University of Virginia in blue text on the right.

Next-Gen Protein Sequencing to Detect Disease-Relevant Proteoforms

Dr. Gloria Sheynkman’s presentation at the Festival of Genomics highlights the importance of detecting protein isoforms for understanding human traits and diseases. She introduces a novel long-read proteogenomics workflow to enhance protein isoform detection. Additionally, she describes how the Platinum® next-gen protein sequencer offers single-molecule protein sequencing technology with high sensitivity and resolution. Platinum provides […]

Beyond the Genome: Unlocking Proteomic Discoveries with Quantum-Si’s Next-Gen Protein Sequencing Technology

Sequencing proteins and correlating amino acid changes to biological function is critical to advancing our understanding of human health and disease. While genomic and transcriptomic data offer insights into potential genetic predispositions and quantify changes in gene expression levels, they do not reflect the immediate changes or responses occurring at the protein level, which are […]

Unleash the Power of Proteomics in Your Lab

Advances in protein identification and characterization are key to unlocking new discoveries in health and disease. In this video, discover how Platinum®, the next-generation protein sequencer is accelerating scientific exploration with an easy-to-use, end-to-end benchtop solution to bring the power of protein sequencing to every lab, everywhere.

RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.