Identification and characterization of protein complexes using a benchtop single-molecule protein sequencer
February 25, 2026
US HUPO 2026 Poster – Accurate and efficient protein identification remains a central challenge in modern biochemistry and molecular biology. Traditional methods often depend on antibody-based detection, which can be limited by antibody availability and specificity, or on complex and costly instrumentation that restricts accessibility for many laboratories. Consequently, there is a growing need for innovative approaches that enable direct and unbiased protein analysis without these constraints. Recent advances in single-molecule protein sequencing have opened new avenues for proteomic analysis, allowing for precise identification of proteins and characterization of protein assemblies. In this study, we performed next-gen protein sequencing (NGPS) on the Platinum®/Platinum® Pro benchtop instruments.