Quantum-Si Marketing Team, Author at Quantum-Si

Measuring Nanobody Kinetics at the Single-Molecule Level

Summary: Antibodies are a paradigm for high-affinity, protein-based binding reagents and are extremely important in biotechnological, diagnostic, and therapeutic applications. Of special interest are nanobodies, recombinant variable domains from heavy-chain-only antibodies. Nanobodies have several advantages: their small molecular weight, superior solubility and stability and clearance rate. One particular use of nanobodies is their use in […]

Multiplexing Nanobody Kinetics Measurements at the Single-Molecule Level

Summary: Single-molecule methods provide useful insights into the intermolecular variations and functional differences of individual molecules and have revealed much about the complexity of biological processes. Today it is possible to monitor binding kinetics at the single molecule level in a highly parallel fashion using zero-mode waveguide (ZMW) arrays. This allows monitoring the binding/unbinding of […]

Library Preparation Kit, V2 – Lys-C Data Sheet

Summary Easily prepare proteins for next-gen protein sequencing (NGPS) on Platinum® in a simple user-friendly workflow. The Platinum instrument, kits, and software contain everything you need to prepare, sequence, and analyze proteins. Library preparation is the initial step in Quantum-Si’s NGPS workflow. The Library Preparation Kit, V2 – Lys-C contains the necessary components to digest […]

Characterizing Far-Flung Extremophiles With Next-Gen Protein Sequencing

Extreme environments that harbor adapted bacteria are widespread — ranging from refrigerators to hot springs. Accordingly, there is massive industrial interest in identifying cold-active, solvent-tolerant, and heat-loving proteins. Thermophiles found in hot springs and the deep sea are sources of diverse biotechnological activity. However, access to compact instrumentation for interrogating proteins in these underexplored sites […]

Beyond the Genome: Unraveling Protein Variability with Quantum-Si’s Next-Gen Protein Sequencing Technology

Summary: Next-gen protein sequencing is a transformational tool for protein science to unlock new insights into the function of proteins in health and diseases. Quantum-Si’s Platinum® technology brings the insights of protein sequencing to every lab with a space-friendly benchtop instrument, a simple end-to-end workflow, and single-molecule resolution that enables detection of protein variants and […]

Real-Time Dynamic Single-Molecule Protein Sequencing on an Integrated Semiconductor Device

Summary:Proteins are the main structural and functional components of biological cells. Assembled and structured through the complexfolding of a specific sequence of amino acids, proteins, along with their dynamic regulation and post-translational modifications (PTMs), largely determine cellular phenotype. New tools to study these changes are necessary. Quantum-Si’s technology uses a proprietary, novel sequencing approach– […]

SelectScience Webinar

Technology Advancements in Next-generation Protein Sequencing with Single Amino Acid Resolution

Time: 8 am PST | 11 am EST | 4 pm BST

Next-Gen Protein Sequencing Advances Variant Identification

In their quest to fully understand the proteome, researchers face an identification challenge: Distinguishing individual proteins among the 20,000-plus proteins and over 1 million proteoforms in human cells. Now a benchtop sequencer provides easy access to the analytical resolution needed to continue mapping protein variation.

ASHG

The meeting will cover a broad spectrum of topics including new technologies, applications, and research to showcase the most compelling genetics and genomics science of the year.

Find QSI at booth #465

NextGen Omics UK

Explore NextGen Omics 2024: Unlocking Future Insights in Omics Research