Missed the lunchtime seminar at World HUPO 2026? Watch it on demand!

In this data-driven and thought-provoking presentation, Quantum-Si CEO, Jeff Hawkins and VP of Market Development, Dave Sloan, PhD, delve into the way single-molecule protein sequencing has evolved over the past several years and provide a first-look at interim data, illustrating how Proteus™, the next-generation protein sequencing platform*, substantially outperforms the current Platinum® Pro system across key sequencing performance metrics, making Proteus a fundamentally unique and improved platform technology rather than an incremental upgrade.

Key points from the presentation:

  • In a 24-protein test panel, Proteus detected all 24 proteins, while Platinum Pro detected an average of 20.3 proteins.
  • Projected ~60× more alignments from a full four-chamber Proteus run compared with a two-chamber Platinum Pro run. 
  • Proteus generated 269,864 amino-acid detections versus 63,366 for Platinum Pro in that study.
  • 1.6× to 2.0× more peptide identifications in protein mixture experiments.
  • 4.8× lower false discovery rate (1.36% Proteus median FDR versus 6.58% Platinum median FDR). 
  • 30× more alignments per chamber than Platinum Pro in control peptide studies.
  • The developmental sequencing chemistry for Proteus currently detects 18 amino acids and all 20 canonical amino acids will be identifiable in 2027.

Watch it now.

* Proteus is currently in development and scheduled for launch in Q2 2027

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