Bioconjugation Process Development Scientist/Senior Scientist

San Diego, California

Company Description

Quantum-Si is pioneering a new generation of technology to create the market of Next Generation Protein Sequencing (NGPS). Similar to Next Generation DNA Sequencing (NGS), which gave us a blueprint of what could happen by studying our DNA, NGPS enables an unbiased view of the proteome through improved scale, resolution, and sensitivity leading to better understanding of disease and improved general health. 

We operate at the intersection of biochemistry, chemistry, hardware, molecular biology, photonics, semiconductor chips, and software with a goal to drive a digital transformation of a $44 billion dollar proteomics market.

Join us on the journey to transform healthcare, motivated by the idea that the products you work on will change the lives of millions of people around the world.

Job Description

  • The Bioconjugation Research Scientist will conduct the preparation, purification, and characterization of bioconjugates of various proteins and peptides with different organic molecules. The candidate will develop and transfer manufacturing protocols to contract manufacturers. The position requires expert knowledge of advanced aspects of synthetic and bioconjugation chemistry, analytical chemistry, separation and purification methods, process development, and scale-up. Proficiency in advanced bioconjugation chemistry and the ability to document and communicate the research results is essential. In addition, the candidate should be proficient using analytical equipment (LC-MS, UV-VIS spectroscopy), including the acquisition and interpretation of data. Familiarity with genetic sequencing and proteomics is desirable but not mandatory


  • Ph.D. in organic/bioorganic chemistry is required, and Postdoctoral experience in Organic/Bioconjugation chemistry is desirable.
  • Experience in Oligonucleotide labeling/purification and characterization
  • Experience in protein/peptide labeling and post-labeling characterization
  • Record of multitasking in a fast-paced environment.
  • Record of completing projects through collaborations

You Deeply Identify with Core Quantum-Si Values:  

  • Team:  We are stronger as a unit and collectively committed to the goal and each other.
  • Accountability:  Be accountable to the goal, the team and yourself.
  • Passion:  We are enthusiastic and dedicated to expanding scientific understanding and its impact.
  • Excellence:  Be aggressive and have a sense of urgency but take pride in each task taken on.
  • Transparency:  We align as an organization and communicate success and challenge.
  • Competitive:  We do not fear but learn from making mistakes.  We play to win!

Additional Information We offer great perks:  

  • Competitive salaried compensation - we value our employees and show it 
  • Equity - we want every employee to be a stakeholder
  • Fully covered medical insurance plan along with a generous company sponsored health reimbursement account, and dental & vision coverage - as a health-tech company, we place great worth on our teams’ well-being
  • Company paid life insurance, short term and long term disability
  • Flexible Paid Time Off - personal responsibility for managing our own time, workload and results plus 14 paid holidays inclusive of MLK Day, Juneteenth, Indigenous People’s Day and Veterans Day
  • Parental Leave - we provide a generous 10 week parental leave and additional 6-8 weeks pregnancy related leave for birthing parents
  • Pre-tax commuter benefits - we make your commute more reasonable 
  • Free onsite meals + kitchen stocked with snacks
  • 401k plan - we facilitate your retirement goals
  • Beautiful office in the heart of San Diego 
  • The opportunity to build a revolutionary healthcare product and save millions of lives! 

For this role, we provide visa assistance for qualified candidates.  

Quantum-Si does not accept agency resumes.  

Quantum-Si is an E-Verify and equal opportunity employer regardless of race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines