Sr. Computational Scientist - Algorithms

Guilford, Connecticut, New York, Remote

Company Description

Quantum-Si is pioneering a new generation of technology to create the market of Next Generation Protein Sequencing (NGPS). Similar to Next Generation DNA Sequencing (NGS), which gave us a blueprint of what could happen by studying our DNA, NGPS enables an unbiased view of the proteome through improved scale, resolution, and sensitivity leading to better understanding of disease and improved general health. 

We operate at the intersection of biochemistry, chemistry, hardware, molecular biology, photonics, semiconductor chips, and software with a goal to drive a digital transformation of a $44 billion dollar proteomics market.

Join us on the journey to transform healthcare, motivated by the idea that the products you work on will change the lives of millions of people around the world.

Job Description

We are looking for an experienced and ambitious computational scientist to join our algorithms team with a focus on signal processing and algorithm development. 

We generate large amounts of complex data that is processed through a pipeline of statistical signal processing layers and a set of probabilistic modules to transduce raw signals into proteomics sequences. The role will require the development of novel algorithms on complex time series data, statistical/probabilistic modeling, and the research and application of advanced pattern recognition techniques.

The ideal candidate will have a deep background in a computational field in science or engineering, have strong knowledge of modern computational libraries in python, be an advanced programmer, and be able to write optimized code that can be run on distributed environments.


  • Ph.D. or M.S. in Computer Science or a related computational/scientific field
  • Track record of developing novel computational approaches and algorithms to solve complex signal processing problems
  • Persistence in investigating hard problems, strong analytical thinking in breaking problems into logical subproblems, ability to devise efficient and flexible strategies to explore such problems from multiple angles, and a strong systematic discipline in documenting findings and hypotheses.
  • Deep understanding of probability and statistics
  • Demonstrated use of good code structure, best practices in software engineering, and computational optimization techniques 
  • Deep knowledge of Python scientific computing libraries (numpy, scipy, sklearn, etc.)
  • Experience with distributed computing environments and writing efficient and highly distributed computational workflows
  • Experience working with large datasets
  • Excellent data summarization and visualization skills

You Deeply Identify with Core Quantum-Si Values:

  • Team:  We are stronger as a unit and collectively committed to the goal and each other.
  • Accountability:  Be accountable to the goal, the team and yourself.
  • Passion:  We are enthusiastic and dedicated to expanding scientific understanding and its impact.
  • Excellence:  Be aggressive and have a sense of urgency but take pride in each task taken on.
  • Transparency:  We align as an organization and communicate success and challenge.
  • Competitive:  We do not fear but learn from making mistakes.  We play to win!
  • Diversity:  Each individual regardless of role makes a difference and impacts our progress.


Additional Information

We offer great perks: 

  • Fully covered medical insurance plan, and dental & vision coverage - as a health-tech company, we place great worth on our teams’ well-being
  • Competitive salaried compensation - we value our employees and show it 
  • Equity - we want every employee to be a stakeholder
  • Pre-tax commuter benefits - we make your commute more reasonable 
  • Free onsite meals + kitchen stocked with snacks.
  • 401k plan - we facilitate your retirement goals
  • Beautiful office near the ocean-front in historic Guilford, Connecticut OR Beautiful office overlooking the Flatiron Building in NYC OR Beautiful office in the heart of San Diego 
  • The opportunity to build a revolutionary healthcare product and save millions of lives! 


Quantum-Si does not accept agency resumes.

Quantum-Si is an E-Verify and equal opportunity employer regardless of race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines.