Principal Engineer, Life Science Devices

Guilford, Connecticut

Company Description

Quantum-Si is developing the world’s first Next Generation Protein Sequencing platform and paving the way for the future of biomedical research.   We are bringing together breakthrough technology at the intersection of hardware, software, biology, and semiconductor chips to change the field of proteomics from analog to digital.

Quantum-Si is a well-funded, rapidly growing biotech company founded by award-winning scientist and highly successful serial entrepreneur, Dr. Jonathan Rothberg.  Quantum-Si benefits from being a 4Catalyzer company, an incubator of biotech and med device companies (most notable Butterfly Network) who have collectively raised over $700 million in funding.

Next generation DNA sequencing transformed every area of life sciences and joining Quantum-Si is an opportunity to define the next generation of protein sequencing through the power of revolutionary technology.  Join us on a journey to maximize global impact, motivated by the idea that our product will change the lives of millions along with the people you love.

Job Description

We are seeking a talented individual to lead a small focused software team that will be responsible for our primary commercial instrument.  You will be responsible for all aspects of the product life cycle, including requirements, design, scheduling, implementation, and test.  We expect you to be a hands-on leader who will make significant contributions to the code.  Experience shipping a product commercially is a must.  The instrument is Linux-based, and utilizes Qt5 for the UI, and GraphQL communications with the cloud.  All software is in-house written in C/C++.  This is a tremendous opportunity, and you will be working alongside world-class scientists and folks who are driven to ship products.   We look forward to discussing your qualifications and how you can help us succeed.


  • Demonstrated Technical leadership
  • Mentoring of junior engineers
  • Project management
  • Working with Test/QA teams
  • C/C++ in a Linux environment
  • Multi-threaded software experience
  • Event-driven UI experience
  • GraphQL & REST experience
  • Shipped commercial products

Additional Information

We offer great perks: 

  • Fully covered medical insurance plan, and dental & vision coverage - as a health-tech company, we place great worth on our teams’ well-being
  • Competitive salaried compensation - we value our employees and show it 
  • Equity - we want every employee to be a stakeholder
  • Pre-tax commuter benefits - we make your commute more reasonable 
  • Free onsite meals + kitchen stocked with snacks
  • 401k plan - we facilitate your retirement goals
  • Beautiful office in the heart of Guilford, CT
  • The opportunity to build a revolutionary healthcare product and save millions of lives! 

All your information will be kept confidential according to EEO guidelines.