Join us for a Lunch + Learn at Scripps Research to learn how Quantum-Si protein sequencing is advancing proteomic research. Discover how using the Platinum® Pro instrument can help you achieve single-molecule resolution for protein characterizatoin and functional analysis...right on your benchtop. Please RSVP so that we can plan enough food for all attendees. Keep reading
Join us for Happy Hour at the Miracle of Science Bar + Grill on December 3, 2025 between 5-8 PM. The evening will include great libations, delicious food and lots of discussions on all things protein analysis with colleagues. And did someone say Raffle? Please RSVP by emailing Joel - [email protected] Keep reading
In this Nature Custom Media webcast, Dr Nigel O’Neil, Co-Founder and Chief Scientific Officer of Arrowsmith Genetics, will discuss his team’s work in oncology drug development, highlighting the technical and biological hurdles encountered when working with conventional protein analysis workflows. Courtesy of Nature Custom Media and sponsored by Quantum-Si Keep reading
Proteins play a vital role in virtually all biological processes, serving as key regulators of cellular functions, disease biomarkers, and therapeutic targets. However, the identification, isolation, and characterization of proteins from biological specimens can be challenging due to their complexity and diversity. Next-Generation Protein Sequencing (NGPS) on Platinum® offers a groundbreaking approach to deeply interrogate individual proteins with high resolution on a user-friendly benchtop platform. When combined with protein separation or enrichment methods, Platinum enables characterization of individual proteins from biological samples, revealing crucial details such as amino acid variants and PTMs. In this application note, we demonstrate a method that combines Sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) protein separation and NGPS on Platinum to identify and characterize serum proteins. This method holds potential for applications beyond serum, offering new insights into disease mechanisms and advancing therapeutic and diagnostic developments. Keep reading
The vast complexity of the proteome currently overwhelms any single analytical technology in capturing the full spectrum of proteoform diversity. In this study, we evaluated the complementarity of two cutting-edge proteomic technologies—single-molecule protein sequencing and individual ion mass spectrometry—for analyzing recombinant human IL-6 (rhIL-6) at the amino acid, peptide, and intact proteoform levels. For single-molecule protein sequencing, we employ the recently released Platinum® instrument. Keep reading
Accelerate decisions and reduce costs… Keep reading
Sequencing Kit V4 is for… Keep reading
Summary Easily prepare proteins for… Keep reading
Nucleic acid-based therapeutics, including antisense… Keep reading